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November 19, 2025

India Breaks New Ground: First Nitric‑Oxide Wound Dressing and Rare‑Earth CRM Developed in Collaboration with BARC

K
Kalpana SharmaCurrent Affairs Editor & Content Lead

Key Highlights

  • Launch of ColoNoX, India’s inaugural nitric‑oxide‑releasing dressing for diabetic foot ulcers.
  • Commercial approval by the Drugs Controller General of India, following successful Phase II/III trials.
  • Introduction of BARC B140, the nation’s first certified reference material for 19 rare‑earth and major elements.
  • Both innovations illustrate the Department of Atomic Energy’s drive to convert nuclear science into societal and strategic benefits.

Detailed Insights

ColoNoX is a collaborative effort between BARC and Cologenesis Pvt. Ltd. The dressing emits nitric oxide, a gas that accelerates tissue regeneration, limits bacterial proliferation, and improves perfusion at the wound site. Phase II/III clinical studies established its safety profile and efficacy, leading to DCGI clearance for market deployment.

The motion for commercialization underscores the DAE’s commitment to affordable, high‑impact health solutions that stem from nuclear‑science research. Dr. Ajit Kumar Mohanty, DAE secretary, emphasized this alignment when announcing the product.

BARC B140 (Ferrocarbonatite) is a certified reference material designed for the validation of analytical methods in rare‑earth mining, extraction, and process control. Developed by the National Centre for Compositional Characterisation of Materials and the Atomic Minerals Directorate, the CRM supplies certified values for thirteen rare‑earth elements and six dominant major elements, thereby enhancing precision in mineral analysis and supporting India’s self‑reliant rare‑earth agenda.

Key Concepts

  • Nitric Oxide (NO) – A reactive gas that, when released locally, modulates vascular tone, reduces infection, and speeds up tissue repair.
  • Certified Reference Material (CRM) – A standard sample with traceable, verified elemental composition used to calibrate analytical instruments.
  • Rare‑Earth Elements (REEs) – A group of seventeen metallic elements crucial for advanced technologies such as electronics, renewable energy, and defense.

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